Adverse Outcome Pathways (AOPs) are conceptual frameworks that tie an initial perturbation (molecular initiat- ing event) to a phenotypic toxicological manifestation (adverse outcome), through a series of steps (key events). They provide therefore a standardized way to map and organize toxicological …

Introduction: Strenuous physical stress induces a range of physiological responses, the extent depending, among others, on the nature and severity of the exercise, a person’s training level and overall physical resilience. This principle can also be used in an experimental set-up by measuring time-dependent …

Samenvatting Introductie: Ondanks behandeling hebben patiënten met diabetes mellitus type 2 (DM2) nog steeds een verhoogd risico om micro- en macrovasculaire complicaties te ontwikkelen. Epidemiologische studies hebben associaties laten zien tussen de inname van monomere en oligomere flavanolen (MOF) …

Background Disorders of the rotator cuff are a common musculoskeletal pain presentation in the general population, and treatment by a physiotherapist is often prescribed. In 2011, 2016, surveys of physiotherapy practice in the United Kingdom (UK) were performed, which reported that advice and exercise …

In dit onderzoek wordt onderzocht wat de behoeften zijn van topsporters van 14 tot 18 jaar binnen de EYSA bij een duale carrière voor topsporters. De onderzoeksvraag om dit te onderzoeken luidt: “Wat zijn de behoeften van de topsporter van 14 tot 18 jaar binnen de EYSA op het gebied van begeleiding …

Background & aims Plasma citrulline concentration is considered to be a marker for enterocyte metabolic mass and to reflect its reduction as may occur during intestinal dysfunction. Strenuous exercise can act as a stressor to induce small intestinal injury. Our previous studies suggest that this comprises …

This report contains: Implementation of social media in business strategies in the retail sector in The Netherlands. The central question is: In what ways has the implementation in 2016 of a new communication strategy with a focus on social media influenced the market share of supermarket PLUS? This …