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An inter-professional student-run medication review programme. Reducing adverse drug reactions in a memory outpatient clinic

a controlled clinical trial

An inter-professional student-run medication review programme. Reducing adverse drug reactions in a memory outpatient clinic

a controlled clinical trial

Samenvatting

ABSTRACT
Background: We investigated if the addition of an inter-professional student-led medication review team (ISP-team) to standard care can increase the number of detected ADRs and reduce the number of ADRs 3 months after an outpatient visit.

Research design and methods: In this controlled clinical trial, patients were allocated to standard care (control group) or standard care plus the ISP team (intervention group). The ISP team consisted of
medical and pharmacy students and student nurse practitioners. The team performed a structured medication review and adjusted medication to reduce the number of ADRs. Three months after the outpatient visit, a clinical pharmacologist who was blinded for allocation performed a follow-up telephone interview to determine whether patients experienced ADRs.

Results: During the outpatient clinic visit, significantly more (p < 0.001) ADRs were detected in the intervention group (n = 48) than in the control group (n = 10). In both groups, 60–63% of all detected ADRs were managed. Three months after the outpatient visit, significantly fewer (predominantly mild
and moderately severe) ADRs related to benzodiazepine derivatives and antihypertensive causing dizziness were detected in the patients of the intervention group.

Conclusions: An ISP team in addition to standard care increases the detection and management of ADRs in elderly patients resulting in fewer mild and moderately severe ADRs

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OrganisatieHogeschool Inholland
AfdelingDomein Gezondheid, Sport en Welzijn
LectoraatInterprofessionele Samenwerking & Medicatieveiligheid
Gepubliceerd inExpert Opinion on Drug Safety Informa UK Limited, trading as Taylor & Francis Group., Vol. 2022, Uitgave: 12, Pagina's: 1511-1520
Datum2022-04-20
TypeArtikel
DOI10.1080/14740338.2022.2069748
TaalEngels

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