Association of proton pump inhibitor use with recurrent falls and risk of fractures in older women: a study of medication use in older fallers
Association of proton pump inhibitor use with recurrent falls and risk of fractures in older women: a study of medication use in older fallers
Samenvatting
Objectives
To examine the association between Proton pump inhibitors (PPIs) use and falls and fractures.
Design
A cross-sectional study.
Setting and participants
400 female patients aged 70 years or older who were consecutively admitted to the Trauma Center Meidling, Vienna, after a fall and who required hospital admission.
Methods
We quantified the strength of the associations between PPI use and falls, and between PPI use and fractures, using a logistic regression.
Results
use of PPIs was significantly associated with risk of recurrent falls (OR 1.92, 95% CI = 1.05–3.50, p = 0.04) as well as with risk of a fracture (OR 2.15, 95% CI 1.10–4.21, p = 0.03).
Conclusions
In conclusion, our results provide further evidence that PPI use may increase risk of falls and fractures in older women and highlight the need for clinicians to reassess the original indication and the need for continuation of PPIs on a regular basis.
| Organisatie | Hogeschool Rotterdam |
| Lectoraat | Kenniscentrum Zorginnovatie |
| Gepubliceerd in | The journal of nutrition, health & aging Vol. 20 (2016), Uitgave: 1, Pagina's: 77-81 |
| Datum | 2016-01-08 |
| Type | Artikel |
| DOI | 10.1007/s12603-016-0679-0 |
| Taal | Engels |
